Affected with madness or insanity.

synonyms: brainsick, crazy, demented, disturbed, mad, sick, unbalanced.

Roget 158: powerless, impotent, unable, incapable, incompetent; inefficient, ineffective; inept; unfit, unfitted; unqualified, disqualified; unendowed; inapt, unapt; crippled, disabled etc. v.; armless^†.    harmless, unarmed, weaponless, defenseless, sine ictu [Lat.], unfortified, indefensible, vincible, pregnable, untenable.    paralytic, paralyzed; palsied, imbecile; nerveless, sinewless^†, marrowless^†, pithless^†, lustless^†; emasculate, disjointed; out of joint, out of gear; unnerved, unhinged; water-logged, on one's beam ends, rudderless; laid on one's back; done up, dead beat, exhausted, shattered, demoralized; graveled etc. (in difficulty) 704; helpless, unfriended^†, fatherless; without a leg to stand on, hors de combat [Fr.], laid on the shelf.    null and void, nugatory, inoperative, good for nothing; ineffectual etc. (failing) 732; inadequate etc. 640; inefficacious etc. (useless) 645.    ... show more

Roget 503: insane, mad, lunatic, loony [Coll.]; crazy, crazed, aliene^†, non compos mentis; not right, cracked, touched; bereft of reason; all possessed, unhinged, unsettled in one's mind; insensate, reasonless, beside oneself, demented, daft; phrenzied^†, frenzied, frenetic; possessed, possessed with a devil; deranged, maddened, moonstruck; shatterpated^†; mad-brained, scatter brained, shatter brained, crackbrained; touched, tetched [Coll.]; off one's head.    [behavior suggesting insanity] maniacal; delirious, lightheaded, incoherent, rambling, doting, wandering; frantic, raving, stark staring mad, stark raving mad, wild-eyed, berserk; delusional, hallucinatory.    [behavior somewhat resembling insanity] corybantic^†, dithyrambic; rabid, giddy, vertiginous, wild; haggard, mazed; flighty; distracted, distraught; depressed; agitated, hyped up; bewildered etc. (uncertain) 475.    mad as a March hare, mad as a hatter; of unsound mind etc. n.; touched in one's head, wrong in one's head, not right in one's head, not in one's right mind, not right in one's wits, upper story; out of one's mind, out of one's wits, out of one's skull [Coll.], far gone, out of one's senses, out of one's wits; not in one's right mind.    fanatical, infatuated, odd, eccentric; hypped^†, hyppish^†; spaced out [Coll.].    imbecile, silly, etc. 499.    ... show more

Roget 732: unsuccessful, successless^†; failing, tripping etc. v.; at fault; unfortunate etc. 735.    abortive, addle, stillborn; fruitless, bootless; ineffectual, ineffective, inconsequential, trifling, nugatory; inefficient etc. (impotent) 158; insufficient etc. 640; unavailing etc. (useless) 645; of no effect.    aground, grounded, swamped, stranded, cast away, wrecked, foundered, capsized, shipwrecked, nonsuited^†; foiled; defeated etc. 731; struck down, borne down, broken down; downtrodden; overborne, overwhelmed; all up with; ploughed, plowed, plucked.    lost, undone, ruined, broken; bankrupt etc. (not paying) 808; played out; done up, done for; dead beat, ruined root and branch, flambe^†, knocked on the head; destroyed etc. 162.    frustrated, crossed, unhinged, disconcerted dashed; thrown off one's balance, thrown on one's back, thrown on one's beam ends^†; unhorsed, in a sorry plight; hard hit.    stultified, befooled^†, dished, hoist on one's own petard; victimized, sacrificed.    wide of the mark etc. (error) 495; out of one's reckoning etc. (inexpectation) 508^†; left in the lurch; thrown away etc. (wasted) 638; unattained; uncompleted etc. 730.    ... show more