Hereditary disease (autosomal recessive) consisting of an error is mucopolysaccharide metabolism; characterized by severe abnormalities in development of skeletal cartilage and bone and mental retardation.

synonyms: dysostosis multiplex, gargoylism, Hurler's syndrome, lipochondrodystrophy.

Polish: maszkaronizm, mukopolisacharydoza typu I, gargoilizm, zespół Hurler, choroba maszkaronów, MPS I