Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs.

synonyms: amyotrophic lateral sclerosis, Lou Gehrig's disease.

Dutch: amyotrofische laterale sclerose
Polish: choroba Lou Gehriga, stwardnienie zanikowe boczne, choroba neuronu ruchowego, choroba Charcota